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Richter transformation continues to be an ominous party for people with CLL, specifically when it's clonally related to the first CLL, mainly because none of the a short while ago accepted novel agents is actually effective. In fact, disease transformation is a comparatively typical cause of failure to reap the benefits of these drugs.ninety,128,129 Histological affirmation is usually suggested as it can guidebook prognosis (i.e., Hodgkin lymphoma and clonally unrelated tumors have more favorable prognosis).
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